Vitamin A deficiency induces sex-specific reward processing alterations through a dysregulation of the mesolimbic dopamine transmission in mice.
Pauline Couty, Sonya Yung, Ilona Dulapt, Loreleï Berger, Adrien Santoro, Lola Hardt, Anna Petitbon, Fabien Ducrocq, Roman Walle, Julien Catanese, Serge Alfos, Jean-Christophe Helbling, Maria-Florencia Angelo, Charlotte Sabran, Patrick Borel, Guillaume Ferreira, Clémentine Bosch-Bouju, Pierre Trifilieff, Katia Touyarot
Neuropsychopharmacol.. 2026-04-04
10.1038/s41386-026-02400-7

The sodium leak channel NALCN in Drd2+ striatal neurons regulates neuronal excitability, locomotion and food-seeking in a sex-dependent manner
Laia Castell, Claire Naon, Angelina Rogliardo, Fabien Ducrocq, Leila Makrini, Alexandra Typou, Maëlle Avrillon, Audrey Mignon, Claire Bernat, Philippe Lory, Federica Bertaso, Arnaud Monteil, Clémentine Bosch-Bouju, Emmanuel Valjent
Neuropsychopharmacology. 2026-02-11
10.1038/s41386-026-02363-9

Reduced Ventral Tegmental Area GABA neuron output contributes to hyperactivity in the activity-based anorexia model in female mice
Fabien Ducrocq, Lianne Delwel, Nick Papavoine, Eileen Brouwer, Karlijn L. Kooij, Inge G. Wolterink-Donselaar, Lisa Drost, Jaimie Hak, Melissa Veendijk, Mieneke C. M. Luijendijk, Frank J. Meye, Roger A. H. Adan
Nat Commun. 2025-12-24
10.1038/s41467-025-67897-w

GLP-1 receptor agonist semaglutide reduces appetite while increasing dopamine reward signaling
Karlijn L. Kooij, Derek IJsbrand Koster, Emma Eeltink, Mieneke Luijendijk, Lisa Drost, Fabien Ducrocq, Roger A.H. Adan
Neuroscience Applied. 2024-01-01
10.1016/j.nsa.2023.103925

Type 2 DiabetesAssociated Mood Disorders: Role of Insulin Resistance in Serotonergic Neurons
HUGO MARTIN, SÉBASTIEN BULLICH, FABIEN DUCROCQ, MARION GRALAND, CLARA OLIVRY, SOPHIE LAYE, BRUNO GUIARD, XAVIER FIORAMONTI
Diabetes. 2020-06-01
10.2337/db20-1758-p