Effect of saffron extract supplementation on mood in healthy adults with subclinical symptoms of depression: a randomized, double-blind placebo-controlled study.
Camille Amadieu, Quentin Leyrolle, Milena Farneti, Andrea Anesi, Eva Bruchet, Juliette Montet, Sandra Dexpert, David Gaudout, Fulvio Mattivi, Line Pourtau, Nathalie Castanon, Lucile Capuron
The American Journal of Clinical Nutrition. 2025-12-01
10.1016/j.ajcnut.2025.09.050

Obesity-induced emotional alterations in mice are associated with impairments of tryptophan metabolism along the kynurenine and indole pathways
Nathalie Castanon, Sylvie Vancassel, Camille Amadieu, Sofia Cussotto, Quentin Leyrolle, Céline Lucas, Antoine Lefevre, Patrick Emond, Anne-Laure Dinel, Lucile Capuron
Brain, Behavior, and Immunity. 2025-11-01
10.1016/j.bbi.2025.106107

Saffron extract interferes with lipopolysaccharide-induced brain activation of the kynurenine pathway and impairment of monoamine neurotransmission in mice
Camille Monchaux de Oliveira, Jennifer Morael, Alexandrine Guille, Camille Amadieu, Sylvie Vancassel, David Gaudout, Lucile Capuron, Line Pourtau, Nathalie Castanon
Front. Nutr.. 2023-10-05
10.3389/fnut.2023.1267839

Exploring the links between gut microbiota and excitatory and inhibitory brain processes in alcohol use disorder: A TMS study
Caroline Quoilin, Camille Amadieu, Fanny Fievez, Nathalie M. Delzenne, Philippe de Timary, Julie Duque, Sophie Leclercq
Neuropharmacology. 2023-03-01
10.1016/j.neuropharm.2022.109384

Liver alterations are not improved by inulin supplementation in alcohol use disorder patients during alcohol withdrawal: A pilot randomized, double-blind, placebo-controlled study
Camille Amadieu, Luca Maccioni, Sophie Leclercq, Audrey M. Neyrinck, Nathalie M. Delzenne, Philippe de Timary, Peter Stärkel
eBioMedicine. 2022-06-01
10.1016/j.ebiom.2022.104033

Microbiota and Metabolite Profiling as Markers of Mood Disorders: A Cross-Sectional Study in Obese Patients
Quentin Leyrolle, Renata Cserjesi, Romane Demeure, Audrey M. Neyrinck, Camille Amadieu, Julie Rodriguez, Olli Kärkkäinen, Kati Hanhineva, Nicolas Paquot, Miriam Cnop, Patrice D. Cani, Jean-Paul Thissen, Laure B. Bindels, Olivier Klein, Olivier Luminet, Nathalie M. Delzenne
Nutrients. 2021-12-29
10.3390/nu14010147

Restoring an adequate dietary fiber intake by inulin supplementation: a pilot study showing an impact on gut microbiota and sociability in alcohol use disorder patients
Camille Amadieu, Valentin Coste, Audrey M. Neyrinck, Victoria Thijssen, Quentin Leyrolle, Laure B. Bindels, Hubert Piessevaux, Peter Stärkel, Philippe de Timary, Nathalie M. Delzenne, Sophie Leclercq
Gut Microbes. 2021-12-20
10.1080/19490976.2021.2007042

N‐3 PUFA deficiency disrupts oligodendrocyte maturation and myelin integrity during brain development
Quentin Leyrolle, Fanny Decoeur, Cyril Dejean, Galadriel Brière, Stephane Leon, Ioannis Bakoyiannis, Emilie Baroux, Tony‐Lee Sterley, Clémentine Bosch‐Bouju, Lydie Morel, Camille Amadieu, Cynthia Lecours, Marie‐Kim St‐Pierre, Maude Bordeleau, Véronique De Smedt‐Peyrusse, Alexandran Séré, Leslie Schwendimann, Stephane Grégoire, Lionel Bretillon, Niyazi Acar, Corinne Joffre, Guillaume Ferreira, Raluca Uricaru, Patricia Thebault, Pierre Gressens, Marie‐Eve Tremblay, Sophie Layé, Agnes Nadjar
Glia. 2021-09-14
10.1002/glia.24088

Dietary fiber deficiency as a component of malnutrition associated with psychological alterations in alcohol use disorder
Camille Amadieu, Sophie Leclercq, Valentin Coste, Victoria Thijssen, Audrey M. Neyrinck, Laure B. Bindels, Patrice D. Cani, Hubert Piessevaux, Peter Stärkel, Philippe de Timary, Nathalie M. Delzenne
Clinical Nutrition. 2021-05-01
10.1016/j.clnu.2021.03.029

Prebiotic effect on mood in obese patients is determined by the initial gut microbiota composition: A randomized, controlled trial
Quentin Leyrolle, Renata Cserjesi, Maria D.G.H. Mulders, Giorgia Zamariola, Sophie Hiel, Marco A. Gianfrancesco, Daphné Portheault, Camille Amadieu, Laure B. Bindels, Sophie Leclercq, Julie Rodriguez, Audrey M. Neyrinck, Patrice D. Cani, Nicolas Lanthier, Pierre Trefois, Jérome Bindelle, Nicolas Paquot, Miriam Cnop, Jean-Paul Thissen, Olivier Klein, Olivier Luminet, Nathalie M. Delzenne
Brain, Behavior, and Immunity. 2021-05-01
10.1016/j.bbi.2021.01.014

Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients
Quentin Leyrolle, Renata Cserjesi, Maria D.G.H. Mulders, Giorgia Zamariola, Sophie Hiel, Marco A. Gianfrancesco, Julie Rodriguez, Daphnée Portheault, Camille Amadieu, Sophie Leclercq, Laure B. Bindels, Audrey M. Neyrinck, Patrice D. Cani, Olli Karkkainen, Kati Hanhineva, Nicolas Lanthier, Pierre Trefois, Nicolas Paquot, Miriam Cnop, Jean-Paul Thissen, Olivier Klein, Olivier Luminet, Nathalie M. Delzenne
Clinical Nutrition. 2021-04-01
10.1016/j.clnu.2020.09.025

Improvement of gastrointestinal discomfort and inflammatory status by a synbiotic in middle-aged adults: a double-blind randomized placebo-controlled trial
Audrey M. Neyrinck, Julie Rodriguez, Bernard Taminiau, Camille Amadieu, Florent Herpin, François-André Allaert, Patrice D. Cani, Georges Daube, Laure B. Bindels, Nathalie M. Delzenne
Sci Rep. 2021-01-29
10.1038/s41598-020-80947-1

Link between gut microbiota and health outcomes in inulin -treated obese patients: Lessons from the Food4Gut multicenter randomized placebo-controlled trial
Sophie Hiel, Marco A. Gianfrancesco, Julie Rodriguez, Daphnée Portheault, Quentin Leyrolle, Laure B. Bindels, Carolina Gomes da Silveira Cauduro, Maria D.G.H. Mulders, Giorgia Zamariola, Anne-Sophie Azzi, Gaetan Kalala, Barbara D. Pachikian, Camille Amadieu, Audrey M. Neyrinck, Audrey Loumaye, Patrice D. Cani, Nicolas Lanthier, Pierre Trefois, Olivier Klein, Olivier Luminet, Jérôme Bindelle, Nicolas Paquot, Miriam Cnop, Jean-Paul Thissen, Nathalie M. Delzenne
Clinical Nutrition. 2020-12-01
10.1016/j.clnu.2020.04.005

Gut Microbiota-Induced Changes in β-Hydroxybutyrate Metabolism Are Linked to Altered Sociability and Depression in Alcohol Use Disorder
Sophie Leclercq, Tiphaine Le Roy, Sonia Furgiuele, Valentin Coste, Laure B. Bindels, Quentin Leyrolle, Audrey M. Neyrinck, Caroline Quoilin, Camille Amadieu, Géraldine Petit, Laurence Dricot, Vanessa Tagliatti, Patrice D. Cani, Kristin Verbeke, Jean-Marie Colet, Peter Stärkel, Philippe de Timary, Nathalie M. Delzenne
Cell Reports. 2020-10-01
10.1016/j.celrep.2020.108238

Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime
Q. Leyrolle, F. Decoeur, G. Briere, C. Amadieu, A. R. A. A. Quadros, I. Voytyuk, C. Lacabanne, A. Benmamar-Badel, J. Bourel, A. Aubert, A. Sere, F. Chain, L. Schwendimann, B. Matrot, T. Bourgeois, S. Grégoire, J. G. Leblanc, A. De Moreno De Leblanc, P. Langella, G. R. Fernandes, L. Bretillon, C. Joffre, R. Uricaru, P. Thebault, P. Gressens, J. M. Chatel, S. Layé, A. Nadjar
Neuropsychopharmacol.. 2020-08-11
10.1038/s41386-020-00793-7

Dietary n-3 long chain PUFA supplementation promotes a pro-resolving oxylipin profile in the brain
C. Rey, J.C. Delpech, C. Madore, A. Nadjar, A.D. Greenhalgh, C. Amadieu, A. Aubert, V. Pallet, C. Vaysse, S. Layé, C. Joffre
Brain, Behavior, and Immunity. 2019-02-01
10.1016/j.bbi.2018.07.025

Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation.
V.F. Labrousse, Q. Leyrolle, C. Amadieu, A. Aubert, A Sere, E. Coutureau, S. Grégoire, L. Bretillon, V. Pallet, P. Gressens, C. Joffre, A. Nadjar, S. Layé
Brain, Behavior, and Immunity. 2018-10-01
10.1016/j.bbi.2018.06.004

Polyphenols from grape and blueberry improve episodic memory in healthy elderly with lower level of memory performance: a bicentric double-blind, randomized, placebo-controlled clinical study.
Julien Bensalem, Stéphanie Dudonné, Nicole Etchamendy, Hermine Pellay, Camille Amadieu, David Gaudout, Séverine Dubreuil, Marie-Eve Paradis, Sonia Pomerleau, Lucile Capuron, Carol Hudon, Sophie Layé, Yves Desjardins, Véronique Pallet
The Journals of Gerontology: Series A. 2018-07-19
10.1093/gerona/gly166

Maternal n-3 polyunsaturated fatty acid dietary supply modulates microglia lipid content in the offspring
Charlotte Rey, Agnès Nadjar, Florent Joffre, Camille Amadieu, Agnès Aubert, Carole Vaysse, Véronique Pallet, Sophie Layé, Corinne Joffre
Prostaglandins, Leukotrienes and Essential Fatty Acids. 2018-06-01
10.1016/j.plefa.2018.04.003

Nutrient biomarker patterns and long-term risk of dementia in older adults
Camille Amadieu, Sophie Lefèvre‐Arbogast, Cécile Delcourt, Jean‐François Dartigues, Catherine Helmer, Catherine Féart, Cécilia Samieri
Alzheimer's & Dementia. 2017-03-16
10.1016/j.jalz.2017.01.025